Publications

Books: 4

  • Costel Moldoveanu, Gheorghiţă Zbancioc, Roxana Tucaliuc, Ana-Maria Zbancioc, Ondina Boiţă, Ionel Mangalagiu, Bazele chimiei organice – Manual de laborator Vol. 1,  Editura Universităţii „Al. I. Cuza”- Iaşi, 2008. ISBN: 978-973-703-387-1.
  • Dorina Iurea, Gheorghiţă Zbancioc, Geanina Mangalagiu, Ionel Mangalagiu, Steroide:compusi naturali si analogi de sinteza. Vol. 2, Editura Universităţii „Al. I. Cuza”- Iaşi, 2009. ISBN: 978-973-703-451-9.
  • I.I. Mangalagiu; R. Danac; C. Moldoveanu; Ghe. Zbancioc. Chimie si toxicologie judiciare. Separatologologie judiciara (217 pag), Ed. „AIT –SRL Laboratory”, 2011, Bucuresti. ISBN: 978-606-8363-09-7×2
  • Danac, R.; Amariucai-Mantu, D.; Antoci, V.; Zbancioc, G.; Mangalagiu, V.; Mangalagiu, I. I., (2021) Microwave Assisted Reactions for Synthesis of Bioactive Azaheterocycles. Current Advances in Chemistry and Biochemistry Vol. 3, 17–50, Ed. Book Publisher International, 2021. https://doi.org/10.9734/bpi/cacb/v3/7477D

Patents: 2

  • patent MD, Nr.4370/C1 2016.04.30 , Agentia de Stat pentru Proprietatea Intelectuala Chisinau, Rep. Moldova (Arîcu Aculina, (MD), Mangalagiu Ionel,(RO), Ciocârlan Alexandru, (MD) Lungu Lidia,(RO), Zbancioc Gheorghiţă, (RO), Vornicu Nicoleta,(RO) “11,12-Bis-p-tolyl-pyridazonyl-drim-5(6),8(9)-diene-7-one exhibiting antifungal and antibacterial properties”
  • patent RO134192-A0/2020 , Oficiul de Stat pentru Inventii si Marci-OSIM Romania – Mangalagiu I.I., Amariucai-Mantu Dorina,  Antoci I. Vasilichia, Zbancioc N. Gheorghita, Moldoveanu C. Costel, Cucu D. Dumitrela, Danac Ramona, Mangalagiu Violeta. “Obtaining class of anthracene-imidazole compounds with anti-tuberculosis effect by performing N-alkylation imidazole and benzimidazole with 9-chloromethyl-anthracene, and subjecting intermediates to quaternization”, Derwent Primary Accession Number: 2020-605892.

Publications:

  1. Mocanu, C.S.; Niculaua, M.; Zbancioc, G.; Mangalagiu, V.; Drochioiu, G.: Novel Design of Neuropeptide-Based Drugs with β-Sheet Breaking Potential in Amyloid-Beta Cascade: Molecular and Structural Deciphers, Int. J. Mol. Sci., 23, 2857, 2022. DOI: 10.3390/ijms23052857
  2. Dumitrela, D.; Amariucai-Mantu, D.; Mangalagiu, V.; Antoci, V.; Zbancioc, G.; Mangalagiu, I.I.: Ultrasound assisted synthesis of hybrid quinoline-imidazole derivatives: a green synthetic approach, RSC Advances, 11, 38297-38301, 2021. DOI: 10.1039/D1RA07484A
  3. Moldoveanu, C; Mangalagiu, I.I.; Zbancioc, G.: Fluorescent azasteroids through ultrasound assisted cycloaddition reactions, Molecules, 26(16), 5098, 2021. DOI: 10.3390/molecules26165098
  4. Antoci, V.; Oniciuc, L.; Amariucai-Mantu, D.; Moldoveanu, C.; Mangalagiu, V.; Amarandei, A.M.; Lungu, C.N.; Dunca, S.; Mangalagiu, I.I.; Zbancioc, G.: Benzoquinoline Derivatives: A Straightforward and Efficient Route to Antibacterial and Antifungal Agents, Pharmaceuticals, 14, 335, 2021. DOI: 10.3390/ph14040335
  5. Antoci, V.; Moldoveanu, C.; Danac, R.; Mangalagiu, V.; Zbancioc, G.: Huisgen 3+2 Dipolar Cycloadditions of Phthalazinium Ylides to Activated Symmetric and Non-Symmetric Alkynes, Molecules, 25, 04416, 2020. DOI: 10.3390/molecules25194416
  6. Zaharia, M.; Mihai, M.; Roman, T.; Zbancioc, G.; Pui, A.; Gradinaru, R.V.; Logigan, C.; Drochioiu, G.: Unusual ferrite induced photohydrolysis of dinitrophenols to nonaromatic and nontoxic derivatives, Journal of Photochemistry & Photobiology, A: Chemistry, 394, 112497, 2020. DOI: 10.1016/j.jphotochem.2020.112497
  7. Al Matarneh, C.; Ciobanu, I.C.; Mangalagiu,V.; Zbancioc, G.; Danac, R.: Microwave Assisted Synthesis of Six Member Ring Azaheterocycles with Antimycobacterial and Anticancer Activity, Chim. (Bucharest), 71(3), 287-293, 2020.
  8. Al Matarneh, C.M.; Amarandi, R.M.; Craciun, A.M.; Mangalagiu, I.I.; Zbancioc, G.; Danac, R.: Design, Synthesis, Molecular Modelling and Anticancer Activities of New Fused Phenanthrolines, Molecules, 25(3), 527, DOI: 10.3390/molecules25030527.
  9. Antoci, V.; Cucu, D.; Zbancioc, G.; Moldoveanu, C.; Mangalagiu, V.; Amăriucăi-Mantu, D.; Aricu, A.; Mangalagiu, I.I.: Bis-(imidazole/benzimidazole)-pyridine derivatives: synthesis, structure and antimycobacterial activity. Part XII, Future Medicinal Chemistry, 12(3), 207-222, 2020, (IF 2018/2019=617),DOI: 10.4155/fmc-2019-0063.
  10. Moldoveanu, C.; Amariucai-Mantu, D.; Mangalagiu, V.; Antoci, V.; Maftei D.; Mangalagiu, I.I.; Zbancioc, G.: Microwave Assisted Reactions of Fluorescent Pyrrolodiazine Building Blocks, Molecules, 24(20), 3760, DOI: 10.3390/molecules24203760
  11. Lupaescu, A; Jureschi, M.; Ciobanu, C.I.; Ion, L.; Zbancioc, G.; Petre, B.A.; Drochioiu, G.: FTIR and MS evidence for heavy metal binding to anti-amyloidal NAP-like peptides, International Journal of Peptide Research and Therapeutics, 25(1), 303-309, 2019. DOI: 10.1007/s10989-018-9672-2
  12. Moldoveanu, C.; Mangalagiu, I.I.; Isac, D.L.; Airinei, A.; Zbancioc, G.: A New Pathway for the Synthesis of a New Class of Blue Fluorescent Benzofuran Derivatives, Molecules, 23(8), 1968, 2018. DOI: 10.3390/molecules23081968
  13. Mangalagiu, I.; Moldoveanu, C.; Zbancioc, G.; Amariucai-Mantu, D.; Vasilache, V.: Theoretical and experimental study on the stability of some 4-(4-chlorophenyl) pyrimidinium ylides, Acta et commentationes, 1(3), 27-43, 2017. ISSN: 2537-6284.
  14. Zaharia, M,; Drochioiu, G.; Zbancioc, G.; Gradinaru, R.: Beyond dinitrophenol interaction with tryptophan-based compounds, Acta Chemica Iasi, 24_1, 43-49, 2016.
  15. Zbancioc, G.; Moldoveanu, C.; Humelnicu, I.; Vasilache, V.; Mangalagiu, I.I.: Pyridine / Quinoline Derivatives Bearing a Imidazole / Benzimidazole Moiety: a LC-MS Approach of Structure Determination, Chim. (Bucharest), 67(8), 1516-1519, 2016
  16. Moldoveanu, C.; Zbancioc, G.; Mantu, D.; Maftei, D.; Mangalagiu, I.I.: The cycloaddition of the benzimidazolium ylides with alkynes: new mechanistic insights, Plos One, 11(5), e0156129, 2016. DOI:10.1371/journal.pone.0156129
  17. Mantu, D.; Antoci, V.; Moldoveanu, C.; Zbancioc, G.; Mangalagiu, I.I.: Hybrid imidazole (benzimidazole) / pyridine (quinoline) derivatives with anticancer and antimycobacterial activity, Journal Of Enzyme Inhibition And Medicinal Chemistry, 31(S2), 96–103, 2016. DOI:10.1080/14756366.2016.1190711
  18. Aricu, A.; Ciocarlan, A.; Lungu, L.; Barba, A.; Shova, S.; Zbancioc, G.; Mangalagiu, I.; D’Ambrosio, M.; Vornicu, N.: Synthesis, antibacterial and antifungal activities of new drimane sesquiterpenoids with azaheterocyclic units, Medicinal Chemistry Research, 25, 2316-2323, 2016. DOI:10.1007/s00044-016-1665-01.277/7=0.1824
  19. Zbancioc, G.; Moldoveanu, C.; Zbancioc, A.M.; Humelnicu, I.; Mangalagiu, I.: New Insights Concerning Microwave Mechanism in Cycloaddition Reaction: Thermal Heating versus Specific Effects of Microwave, Roum. Chim., 61(4-5), 441-444, 2016. ISSN: 0035-3930.
  20. Zbancioc, A.M.; Tataringa, G.; Jitareanu, A.; Rotinberg, P.; Mihai, C.T.; Zbancioc, G.; Miron, A.; Luca, C.M.: Structure and Cytotoxic Activity of Some Dihydroxyacetophenone Derivatives, Chim. (Bucharest), 66(10), 1603-1606, 2015.
  21. Zbancioc, G.; Mangalagiu, I.; Moldoveanu, C.: Ultrasound assisted synthesis of imidazolium salts: An efficient way to ionic liquids, Ultrasonics Sonochemistry, 23(c), 376-384, 2015. DOI: 10.1016/j.ultsonch.2014.10.028
  22. Zbancioc, Ghe; Moldoveanu, C.; Zbancioc, A.M.; Mangalagiu, I.: Microwave Assisted Synthesis of New Pyrrolopyridazine Derivatives with Acetophenone Skeleton. Part IV, Current Microwave Chemistry, 1(1), 41-46, DOI: 10.2174/2213335601666140210211520
  23. Zbancioc, A.M.; Miron, A.; Tuchilus, C; Rotinberg, P.; Mihai, C.T.; Mangalagiu, I.;Zbancioc, Ghe: Synthesis and in vitro analysis of novel dihydroxyacetophenone derivatives with antimicrobial and antitumor activities, Medicinal Cheminstry, 10(5), 476-483, 2014. DOI: 2174/15734064113096660070
  24. Zaharia, M.; Borhan, A.; Gherca, G.; Pui, A.; Gradinaru,R.; Zbancioc, G.; Drochioiu, G.: Letter: Study on the mechanism of ferrite-associated dinitrophenol photodegradation, Eur J Mass Spectrom, 20, 193-197, 2014. doi: 10.1255/ejms.1267
  25. Kuchkova, K.; Aricu, A.; Secara, E.; Barba, A.; Vlad, P.; Ungur, N.; Tuchilus, C; Shova, S.; Zbancioc, G.; Mangalagiu, I.: Design, synthesis, and antimicrobial activity of some novel homodrimane sesquiterpenoids with diazine skeleton, Medicinal Chemistry Research, 23, 1559-1568, 2014. DOI: 10.1007/s00044-013-0720-3
  26. Zbancioc, G.; Zbancioc, A.M.; Mangalagiu, I.: Ultrasound and microwave assisted synthesis of dihydroxyacetophenone derivatives with or without 1,2-diazine skeleton, Ultrasonics Sonochemistry, 21(2), 802-811, 2014. DOI: 1016/j.ultsonch.2013.09.012
  27. Habasescu, L.; Zbancioc, G.; Gradinaru, R.V.; Murariu, M.; Ferencz, L.; Drochioiu, G.: Copper binding to SG and EE peptides as a function of pH. Implication for understanding amyloindogenesis, Roum. Chim., 58(6), 501-509, 2013. ISSN: 0035-3930.
  28. Zbancioc, A.M.; Miron, A.; Moldoveanu, C.; Zbancioc, Ghe: Imidazolium Salts with Dihydroxyacetophenone Skeleton with Anticipated Anticancer Activity. Part II, Chim. (Bucharest), 64 (6), 584-586, 2013.
  29. Maftei, D.; Zbancioc, G.; Humelnicu, I.; Mangalagiu, I.I.: Conformational Effects on the Lowest Excited States of Benzoyl-Pyrrolopyridazine. Insights from PCM Time-Dependent DFT, Phys. Chem. A, 117(15), 3165-3175, 2013. DOI: 10.1021/jp311396m
  30. Kuchkova, K.; Aricu, A.; Barba, A.; Vlad, P.; Shova, S.; Secara, E.; Ungur, N.; Zbancioc, G.; Mangalagiu, I.: An Efficient and Straightforward Method to New Organic Compounds: Homodrimane Sesquiterpenoids with Diazine Units, Synlett, 24, 697-700, 2013. doi: 10.1055/s-0032-1318253
  31. Zbancioc, G.; Drochioiu, G.; Mangalagiu, I.: Nicotine and tobacco alkaloids: A GC-MS a Part 2: The tobacco and smoking, International Journal of Criminal Investigation, 2(4), 251-257, 2012.
  32. Zbancioc, G.; Gradinaru, R.; Drochioiu, G.; Mangalagiu, I.: Nicotine and tobacco alkaloids: A GC-MS approach, International Journal of Criminal Investigation, 2(1), 3-10, 2012.
  33. Zbancioc, G.; Florea, O.; Jones, P.G.; Mangalagiu, I.I.: An efficient and selective way to new highly functionalized coronands or spiro derivatives using ultrasonic irradiation, Sonochem, 19(3), 399–403, 2012. DOI:10.1016/j.ultsonch.2011.08.001.
  34. Drochioiu, G.; Sandu, I.; Gradinaru, R.; Zbancioc, G.; Mangalagiu, I.: Ninhydrin-based forensic investigations: II. Cyanide analytical toxicology, International Journal of Criminal Investigation, 1(4), 213-226, 2011.
  35. Zbancioc, G.; Moldoveanu, C.; Gradinaru, R.; Drochioiu, G.; Olteanu, G.; Mangalagiu, I.: The metabolism of drugs / toxics in the body. Case study: BZP, International Journal of Criminal Investigation, 1(1), 17-24, 2011.
  36. Tucaliuc, R.; Cotea, V.V.; Moldoveanu, C.; Zbancioc, G.; Deleanu, C.; Jones, P.G.; Mangalagiu, I.I.: An efficient and selective route to hybrid trifluoromethyl-substituted γ-lactones or fused nitrogen derivatives via cascade reactions, Tetrahedron Letters, 52, 6439–6442, 2011. DOI:10.1016/j.tetlet.2011.09.093. 2,618/7=0.374
  37. Gradinaru, R.; Ionas, A.; Pui, A.; Zbancioc, G.; Drochioiu, G.: Interaction of inorganic mercury with CoA-SH and acyl-CoAs, Biometals, 24, 1115–1121, 2011. DOI: 10.1007/s10534-011-9472-z. 3,172/5=0.6344
  38. Murariu, M.; Dragan, E. S.; Adochitei, A.; Zbancioc, G.; Drochioiu, G.: Silver-induced conformational changes of polypeptides: A CD study, J. Pept. Sci., 17, 512-519, 2011. 1,807/5=0.3614
  39. Mantu, D.; Luca, M.C, Moldoveanu, C.; Zbancioc, Ghe.; Mangalagiu I. I.:  Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II, Eur. J. Med. Chem, 45, 5164-5168, 2010. ISSN: 0223-5234. 3,269/5=0.6539
  40. Zbancioc, A.M.; Zbancioc, Ghe; Tanase, C. Miron, A.; Mangalagiu I. I.: Design, synthesis and in vitro anticancer activity of a new class of dual DNA intercalators, Lett. Drug Des. Discov., 7, 644-649, 2010. Bentham Science Publishers, ISSN: 1570-1808. 0,786/5=0.1572
  41. Zbancioc, G; Huhn, T.; Groth, U; Deleanu, C.; Mangalagiu, I; Pyrrolopyridazine derivatives as blue organic luminophores: synthesis and properties. Part 3, Tetrahedron, 66, 4298-4306, 2010. ISSN: 0040-4020. 3.219/5=0.6438
  42. Zbancioc, G; Mangalagiu, I; Pyrrolopyridazine derivatives as blue organic luminophores: synthesis and properties. Part 2, Tetrahedron, 66, 278-282, 2010. ISSN: 0040-4020. 3.219/2=1.6095
  43. Zbancioc, G; Zbancioc, A.M.; Mangalagiu, I.I.; Environmentally friendly Methods for synthesis of new aromatic bisesters, Synthetic commun., 40(15), 2201-2208, 2010. ISSN: 0039-7911. 0.961/3=0.3203
  44. Zbancioc, G; Zbancioc, A.M.; Mantu, D.; Miron, A.; Tanase, C.; Mangalagiu, I.I.; Ultrasounds assisted synthesis of highly functionalized acetophenone derivatives in heterogeneus catalysis, Rev. Roum. Chim., 55(11-12) , 983-987, 2010. ISSN: 0035-3930. 0.263/6=0.04383
  45. Zbancioc, G; Zbancioc, A.M.; Mangalagiu, I.I.; Microwave assisted reactions of aromatic bisesters in liquid phase, Rev. Roum. Chim., 55(2) , 117-122, 2010. ISSN: 0035-3930. 0.263/3=0.08766
  46. Zbancioc, Ghe.; Bejan, V.; Risca, M.; Moldoveanu, C.; Mangalagiu, I.; Microwave assisted reactions of some azaheterocyclic compounds, Molecules 14, 403-411; doi:10.3390, 2009. 1.738/5=0.3476
  47. Balan A.M.; Florea O.; Moldoveanu, C.; Zbancioc Ghe; Iurea, D.; Mangalagiu I. I.: Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity, European Journal of Medicinal Chemistry, 44, 2275-2279, 2009. 3,269/6=0.5448
  48. Balan, A.M.; Zbancioc, G.; Bentea, E.; Carja, I.; Ungureanu, M; Tuchilus, C; Mangalagiu, I; Synthesis and antimicrobial activity of new aromatic esters of potential interest in supramolecular chemistry, Rev. Chim., 60 (10), 1021-1024, 2009. 0,552/7=0.0788
  49. Drochioiu, G.; Adochitei, A; Habasescu, L; Zbancioc, G; Pui, A; Gradinaru, R.;Rusu, E; CD and FT-IR study of some adducts of albumin with toxic dinitophenyl derivatives, Bull. Instit. Polith. Iasi, Sectia Chimie si Inginerie Chimica, Tomul LV (LIX), Fasc. 4, 23-28, 2009.
  50. Murariu, M.; Stela, Dragan, E.S.; Adochitei, A; Habasescu, L; Zbancioc, G; Pui, A; Drochioiu, G.; Conformational changes of peptides on binding metals: CD & FT-IR studies, Bull. Instit. Polith. Iasi, Sectia Chimie si Inginerie Chimica, Tomul LV (LIX), Fasc. 4, 89-94, 2009.
  51. Mangalagiu, I.I.; Florescu, M.; Zbancioc, G.; Caprosu, M.: Synthesis of new 1,2-diazine nanomaterials through conventional and nonconventional methods, Journal of Physics: Conferince Series, 2007, 61, 484-486.
  52. Zbancioc, G.; Mangalagiu, I.: Microwave-assisted synthesis of highly fluorescent pyrrolopyridazine derivatives, SynLett, 2006, (05), 0804-0806. 2,838/2=1.419
  53. Dima, St.; Zbancioc, G.; Mangalagiu, I. I.: The cycloaddition reactions of 1-methylphthalazinium ylides to non symetrical substituted alkynes in solid-phase and interphasic catalysis, J. Serb. Chem. Soc., 2006, 71 (2), 103-110. 0.423/3=0.141
  54. Risca, I.M.; Zbancioc, G.; Moldoveanu, C.; Drochioiu, G.; Mangalagiu, I.: Effect of some new monoquaternary salts of diazine on germination and seedling growth of Norway spruce (Picea abies (L.) Karsten), Romanian Biotechnological Letters, 2006, 11(1), 2563-2568.
  55. Zbancioc, G.; Caprosu, M.; Moldoveanu, C.; Mangalagiu, I.: Microwave assisted synthesis for dimers via [3+3] dipolar cycloaddition, Arkivok, 2005, (x), 189-198. 0.694/4= 0.1735
  56. Moldoveanu, C.; Mangalagiu, G.; Zbancioc, G.; Drochioiu, G.; Caprosu, M.; Mangalagiu, I.I.: 4-(4-Chlorophenyl)pyrimidinium ylides, 1. Structure, stability, reactivity, Arkivoc, 2005, (i), 7-19. 0.694/6=0.1156
  57. Zbancioc, G.; Caprosu, M.; Moldoveanu, C.; Mangalagiu, I.: Microwave assisted 1-3 dipolar cycloaddition reactions of 4-halophenyl-phthalazinium ylides, Rev. Roum. Chim., 2005, 50(5), 353-358. 0.226/4=0.0565
  58. Mangalagiu, I.; Risca, I.M.; Maftei, M.; Zbancioc, G.; Murariu, M.; Drochioiu, G.: Effect of some new monoquaternary salts of pyridazine on germination and seedling growth of wheat, Romanian Biotechnological Letters, 2005, 10(6), 2495-2501.
  59. Caprosu, M.; Zbancioc, G.;  Moldoveanu, C.; Mangalagiu, I.: 1-3 dipolar cycloaddition reactions of 4- halophenyl-phthalazinium ylides to activated alkenes and alkynes, Collect. Czech. Chem. Commun., 2004, 69 (2), 426-434. 1.062/4=0.2655
  60. Mangalagiu, I.I.; Caprosu, M.; Mangalagiu, G.; Zbancioc, G.; Petrovanu, M.: Diazinium carbalkoxy methylides,  Arkivoc, 2002, 3(II), 73-79. 0.694/5=0.1388
  61. Zbancioc, G.; Mangalagiu, G.; Dima, St.; Moldoveanu, C.; Petrovanu, M.; Mangalagiu, I.: Microwave irradiation in synthesis of azinium salts,  Anall. Sci. Univ. Iassi, 2002, 10 (1), 146-149.
  62. Mangalagiu, I.; Mangalagiu, G.; Dima, St.; Moldoveanu, C.; Zbancioc, Gh.; Petrovanu, M.: Study of the basicity of some 4-methyl-pyrimidinium ylides, Anall. Sci. Univ. “Al. I. Cuza” Iassi, 2001, 9(s1c), 115-118.

Citations in international journals: more than 700 citations – h-index – 15.

List of conference: more than 140 international and national conferences;

Research’s grants

  • 3 grants as project manager:
  1. Grant TE; cod UEFISCDI PN-III-P1-1.1-TE-2016-1205, period: 2018- 2020; Finance by UEFISCDI, Romanian Ministry of Education and Research; Project manager: Conf. dr. Gheorghiţă ZBANCIOC; Grant value: 450.000 RON; Project title: New Polyfunctional Azasteroids Mimics: fluorescent and biologically active compounds
  2. Grant Bilateral România-Rep. Moldova, 682/2013, period: 2013–2014; Finance by UEFISCDI, Romanian Ministry of Education and Research; Project managers: Conf. dr. Gheorghiţă ZBANCIOC/CP I. dr. Alexandru Ciocârlan, Academy of Science of Rep. Moldova; Grant value: 29.000 RON;Project title: Sinteza compuşilor noi biologic activi cu unităţi structurale terpenice şi heterociclice
  3. Grant TD, no. 27693/2005, cod CNCSIS 348, period: 2005-2006; Financed by CNCSIS, Romanian Ministry of Education and Research; Project manager: Prep. drd. Gheorghiţă ZBANCIOC; Grant value: a) anul 2005: 2950 € b) anul 2006: 1780 €; Project title: Microwave assisted reactionin pyridazinium and phthalazinium ylides
  • 10 grants as associate (with Romanian Ministry of Education and Research)